Article
Association of polymorphisms in the collagen region of human SP-A1 and SP-A2 genes with pulmonary tuberculosis in Indian population.
Clinical chemistry and laboratory medicine - 1 Oct 2002
Madan Taruna, Saxena Shweta, Murthy Kolluri J R, Muralidhar Kambadur, Sarma Puranam Usha
Abstract excerpt
Surfactant protein A (SP-A) binds to and modulates phagocytosis of Mycobacterium tuberculosis by macrophages. We investigated the relationship between polymorphisms in the collagen regions of SP-A1 and SP-A2 genes and pulmonary tuberculosis. In the present study, seven single nucleotide polymorphisms (SNPs) (4 exonic and 3 intronic) have been identified in the collagen regions of SP-A1 and SP-A2 genes in Indian...
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