Article
A degenerate type III secretion system from septicemic Escherichia coli contributes to pathogenesis.
Journal of bacteriology - 1 Dec 2005
Ideses Diana, Gophna Uri, Paitan Yossi, Chaudhuri Roy R, Pallen Mark J, Ron Eliora Z
Abstract excerpt
The type III secretion system (T3SS) is an important virulence factor used by several gram-negative bacteria to deliver effector proteins which subvert host cellular processes. Enterohemorrhagic Escherichia coli O157 has a well-defined T3SS involved in attachment and effacement (ETT1) and critical for virulence. A gene cluster potentially encoding an additional T3SS (ETT2), which resembles the SPI-1 system in...
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