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A highly conserved complete accessory Escherichia coli type III secretion system 2 is widespread in bloodstream isolates of the ST69 lineage.

Scientific reports - 5 Mar 2020

Fox Stephen, Goswami Cosmika, Holden Matthew, Connolly James P R, Mordue James, O'Boyle Nicky, Roe Andrew, Connor Martin, Leanord Alistair, Evans Tom J

Abstract excerpt

Bacterial type III secretion systems (T3SSs) play an important role in pathogenesis of Gram-negative infections. Enteropathogenic and enterohemorrhagic Escherichia coli contain a well-defined T3SS but in addition a second T3SS termed E. coli T3SS 2 (ETT2) has been described in a number of strains of E. coli. The majority of pathogenic E. coli contain elements of a genetic locus encoding ETT2, but which has...

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PMID: 32139768
DOI: 10.1038/s41598-020-61026-x
PMCID: PMC7058095

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