Article
Lack of association of human leukocyte antigen-B7 with COPD and rate of decline in lung function.
Respiratory medicine - 1 Dec 2005
Kasuga Ikuma, Ruan Jian, Connett John E, Anthonisen Nicholas R, Sandford Andrew J
Abstract excerpt
BACKGROUND: Although variation in the human leukocyte antigen (HLA) locus is associated with various diseases, there have been a limited number of studies that have examined the possible role of HLA in chronic obstructive pulmonary disease (COPD). Only HLA-B7 has been shown to be correlated with low forced expiratory volume in 1s (FEV1) in Caucasians; however, this finding has not been replicated. The aim of this...
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