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Article

Efficient differentiation of Mycobacterium tuberculosis strains of the W-Beijing family from Russia using highly polymorphic VNTR loci.

European journal of epidemiology - 1 Jan 2005

Surikova O V, Voitech D S, Kuzmicheva G, Tatkov S I, Mokrousov I V, Narvskaya O V, Rot M A, van Soolingen D, Filipenko M L

Abstract excerpt

The W-Beijing family is a widespread Mycobacterium tuberculosis clonal lineage that frequently causes epidemic outbreaks. This family is genetically homogeneous and conserved, so ETR-VNTR (exact tandem repeat-variable number of tandem repeats) typing is insufficient for strain differentiation, due to a common ETR-A to E profile (42435). This leads to the false clustering in molecular epidemiological studies,...

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PMID: 16284875
DOI: 10.1007/s10654-005-3636-5

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