Article
Identification of serovar-specific single-nucleotide polymorphisms of C. Trachomatis omp1 gene.
Bulletin of experimental biology and medicine - 1 Aug 2005
Sharkeev V I, Torshin I Y, Shkarupeta M M, Akopian T A, Lazarev V N, Govorun V M
Abstract excerpt
Complete sequences of omp1 gene encoding chlamydial main outer membrane protein were analyzed in 76 clinical strains of C. trachomatis. Thirty-four serovar-specific single-nucleotide polymorphisms were identified, 20 of them meet two criteria: unique position of the nucleotide and unique nucleotide substitution. Evaluation of serovar-specific single-nucleotide polymorphisms of omp1 gene can appreciably simplify...
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