Article
Strain improvement studies on production of cephalosporin C from Acremonium chrysogenum ATCC 48272.
Hindustan antibiotics bulletin - 1 Jan 2000
Ellaiah P, Kumar J Prem, Saisha V, Sumitra J J, Vaishali P
Abstract excerpt
Strain development for antibiotic production has been an essential prerequistie for efficient production process. Studies were carried out to produce high antibiotic yield strain by using UV and N-methyl-N1-nitro-nitrosoguanidine (NTG) as mutagens. A superior mutant (PNTG-22) with a productivity of 2.4 time (810-1995 microg/ml higher than, the parent strain was produced.
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