Article
Sacred disease secrets revealed: the genetics of human epilepsy.
Human molecular genetics - 15 Oct 2005
Turnbull Julie, Lohi Hannes, Kearney Jennifer A, Rouleau Guy A, Delgado-Escueta Antonio V, Meisler Miriam H, Cossette Patrick, Minassian Berge A
Abstract excerpt
Neurons throughout the brain suddenly discharging synchronously and recurrently cause primarily generalized seizures. Discharges localized awhile in one part of the brain cause focal-onset seizures. A genetically determined generalized hyperexcitability had been predicted in primarily generalized seizures, but surprisingly the first epilepsy gene discovered, CHRNA4, was in a focal (frontal lobe)-onset syndrome....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.