Article
The hidden genetics of epilepsy-a clinically important new paradigm.
Nature reviews. Neurology - 1 May 2014
Thomas Rhys H, Berkovic Samuel F
Abstract excerpt
Understanding the aetiology of epilepsy is essential both for clinical management of patients and for conducting neurobiological research that will direct future therapies. The aetiology of epilepsy was formerly regarded as unknown in about three-quarters of patients; however, massively parallel gene-sequencing studies, conducted in a framework of international collaboration, have yielded a bounty of discoveries...
Topics
- DNA Copy Number Variations
- Epilepsy
- Family Health
- Genetic Testing
- Genome
- Humans
- Mutation