Article
Lack of association between the IL13 variant Arg110Gln and susceptibility to cedar pollinosis in a Japanese population.
International archives of allergy and immunology - 1 Jan 2006
Cheng Lei, Hirota Tomomitsu, Enomoto Tadao, Tamari Mayumi, Akahoshi Mitsuteru, Matsuda Akira, Shimizu Makiko, Takahashi Naomi, Enomoto Keisuke, Yamasaki Akiko, Mao Xiao-Quan, Hopkin Julian M, Shirakawa Taro
Abstract excerpt
BACKGROUND: Interleukin (IL)-13 has come to be appreciated as a molecule critically involved in allergic inflammatory responses. Recent studies revealed that a common variant in the coding region of the IL13 gene, Arg110Gln, has been implicated in the development of asthma and atopy. METHODS: To assess whether the IL13 variant Arg110Gln is associated with cedar pollinosis, one of the most common atopic diseases...
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