Article
Impact of genes related to immune tolerance and inflammation (tumour necrosis factor-alpha, interleukin-6) on blood pressure, protein excretion and oedema in pregnancy.
Journal of hypertension - 1 Dec 2005
Pfab Thiemo, Chen You-Peng, Slowinski Torsten, Richter Claus M, Godes Michael, Arck Petra C, Halle Horst, Hocher Berthold
Abstract excerpt
OBJECTIVE: To test the hypothesis that genetically determined alterations of maternal immune tolerance to a foetal semi-allograft are important for the pathogenesis of hypertensive disorders in pregnancy. DESIGN: A genetic association study was performed to analyse the impact of genetic polymorphisms known to be involved in immune tolerance on markers of pre-eclampsia. SETTING: The study was conducted at the...
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