Article
A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex.
Molecular biology of the cell - 1 Jan 2006
Dunn Cory D, Lee Marina S, Spencer Forrest A, Jensen Robert E
Abstract excerpt
Unlike many other organisms, the yeast Saccharomyces cerevisiae can tolerate the loss of mitochondrial DNA (mtDNA). Although a few proteins have been identified that are required for yeast cell viability without mtDNA, the mechanism of mtDNA-independent growth is not completely understood. To probe the relationship between the mitochondrial genome and cell viability, we conducted a microarray-based, genomewide...
Topics
- ATP-Dependent Proteases
- Adenosine Triphosphatases
- DNA, Mitochondrial
- Genetic Testing
- Genome, Fungal
- Metalloendopeptidases
- Mitochondrial Proteins
- Mutation
- Phenotype
- Protein Binding
- Protein Subunits