Article
No association of leukemia inhibitory factor (LIF) DNA polymorphisms with multiple sclerosis.
Journal of neuroimmunology - 1 Feb 2006
Vanderlocht Joris, Burzykowski Tomasz, Somers Veerle, Stinissen Piet, Hellings Niels
Abstract excerpt
Neuropoietins such as leukemia inhibitory factor (LIF) have been shown to ameliorate experimental autoimmune encephalomyelitis (EAE) and promote oligodendrocyte survival in vivo. We tested whether two previously described LIF polymorphisms are associated with MS by genotyping these single nucleotide polymorphisms (SNPs) in a group of MS patients (n=110), rheumatoid arthritis (RA) patients (n=120) and healthy...
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