Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isolation and characterization of the leucine-rich proteoglycan nyctalopin gene (cNyx) from chick.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2005

Bech-Hansen N Torben, Cockfield Josh, Liu Dan, Logan C Cairine

Abstract excerpt

We describe the isolation and molecular characterization of the chick ortholog of nyctalopin (NYX), the gene responsible for X-linked complete congenital stationary night blindness (CSNB1, also known as cCSNB). Chick Nyx (cNyx) comprises four exons spanning approximately 6.2 kb on Chromosome 1 and encodes a protein of 473 amino acids that shares 55% identity overall with its human counterpart. cNyx is expressed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern
Share to Chickens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Diseases, X-Linked

Share to In Situ Hybridization

Share to Night Blindness

Share to Proteoglycans

Share to Retina

Share to Sequence Alignment

Source

Identifiers

PMID: 16261423
DOI: 10.1007/s00335-005-0018-y

Genes

NYX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isolation and characterization of the leucine-rich proteoglycan nyctalopin gene (cNyx) from chick.PMID 16261423Read ↗

A novel homozygous splice site mutation in NALCN identified in siblings with cachexia, strabismus, severe intellectual disability, epilepsy and abnormal respiratory rhythm.Semantic proximity Read ↗

Identification and functional validation of a novel disease-causing variant in the noncoding region of NYX.Semantic proximity Read ↗

Novel frameshift mutation in NYX gene in a Russian family with complete congenital stationary night blindness.Semantic proximity Read ↗

Identification of the gene and the mutation responsible for the mouse nob phenotype.Semantic proximity Read ↗

A naturally-occurring mutation in Cacna1f in a rat model of congenital stationary night blindness.Semantic proximity Read ↗

A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome.Semantic proximity Read ↗

Optic Nerve Hypoplasia Is a Pervasive Subcortical Pathology of Visual System in Neonates.Semantic proximity Read ↗

Congenital stationary night blindness in mice - a tale of two Cacna1f mutants.Semantic proximity Read ↗

A common NYX mutation in Flemish patients with X linked CSNB.Semantic proximity Read ↗

Whole-exome sequencing identifies mutations in GPR179 leading to autosomal-recessive complete congenital stationary night blindness.Semantic proximity Read ↗

NYX (nyctalopin on chromosome X), the gene mutated in congenital stationary night blindness, encodes a cell surface protein.Semantic proximity Read ↗

Human microphthalmia associated with mutations in the retinal homeobox gene CHX10.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.