Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pathways of galactose metabolism by galactosemics: evidence for galactose conversion to hepatic UDPglucose.

Molecular genetics and metabolism - 1 Feb 2006

Segal Stanton, Wehrli Suzanne, Yager Claire, Reynolds Robert

Abstract excerpt

To determine if classic galactosemics have residual galactose-1-phosphate uridyltransferase (GALT) activity to explain their considerable ability to oxidize galactose over 24 h, we devised a method for assessing their ability to form hepatic UDPglucose (UDPglu), an intermediate in the normal Leloir pathway of galactose metabolism. The protocol involved the single oral administration of 7 mg/kg [2-13C]galactose...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetaminophen
Share to Blood Glucose
Share to Carbon Dioxide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carbon Radioisotopes

Share to Galactose

Share to Galactosemias

Share to Magnetic Resonance Spectroscopy

Share to UTP-Hexose-1-Phosphate Uridylyltransferase

Source

Identifiers

PMID: 16260165
DOI: 10.1016/j.ymgme.2005.09.012

Genes

GALT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pathways of galactose metabolism by galactosemics: evidence for galactose conversion to hepatic UDPglucose.PMID 16260165Read ↗

Evidence for alternate galactose oxidation in a patient with deletion of the galactose-1-phosphate uridyltransferase gene.Semantic proximity Read ↗

Current and Future Treatments for Classic GalactosemiaSemantic proximity Read ↗

Fluorinated Galactoses Inhibit Galactose-1-Phosphate Uridyltransferase and Metabolically Induce Galactosemia-like Phenotypes in HEK-293 Cells.Semantic proximity Read ↗

A galactose-1-phosphate uridylyltransferase-null rat model of classic galactosemia mimics relevant patient outcomes and reveals tissue-specific and longitudinal differences in galactose metabolism.Semantic proximity Read ↗

Galactose breath testing distinguishes variant and severe galactose-1-phosphate uridyltransferase genotypes.Semantic proximity Read ↗

Hereditary galactosemia.Semantic proximity Read ↗

Pathophysiology and targets for treatment in hereditary galactosemia: A systematic review of animal and cellular models.Semantic proximity Read ↗

Galactosemia: The good, the bad, and the unknownSemantic proximity Read ↗

The 1-13 C galactose breath test in GALT deficient patients distinguishes NBS detected variant patients but does not predict outcome in classical phenotypes.Semantic proximity Read ↗

In vivo oxidation of [13C]galactose in patients with galactose-1-phosphate uridyltransferase deficiency.Semantic proximity Read ↗

Urine and plasma galactitol in patients with galactose-1-phosphate uridyltransferase deficiency galactosemia.Semantic proximity Read ↗

GALT Deficiency GalactosemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.