Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Individual differences in drug dependence in rats: the role of genetic factors and life events.

European journal of pharmacology - 5 Dec 2005

Ellenbroek Bart A, van der Kam Elizabeth L, van der Elst Martine C J, Cools Alexander R

Abstract excerpt

Drug dependence and addiction is a chronic mental illness that has far reaching consequences for society in terms of economic loss, health costs and judicial problems. A crucial question in drug addiction, is what factors are involved in its aetiology, and especially what mediates the shit from u...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloid Precursor Protein Secretases
Share to Endopeptidases
Share to Environment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Risk Factors

Share to Species Specificity

Share to Substance-Related Disorders

Source

Identifiers

PMID: 16253227
DOI: 10.1016/j.ejphar.2005.09.032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16253227-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Individual differences in drug dependence in rats: the role of genetic factors and life events.PMID 16253227Read ↗

Genes and addiction.Semantic proximity Read ↗

Genetic background, nature of event, and time of exposure to event direct the phenotypic expression of a particular genotype. A study with apomorphine-(un)susceptible Wistar rats.Semantic proximity Read ↗

Apomorphine susceptibility and animal models for psychopathology: genes and environment.Semantic proximity Read ↗

Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction.Semantic proximity Read ↗

Vertical shifts in self-administration dose-response functions predict a drug-vulnerable phenotype predisposed to addiction.Semantic proximity Read ↗

[Are we genetically predisposed to addictions?].Semantic proximity Read ↗

Apomorphine-susceptible rats and apomorphine-unsusceptible rats differ in the tyrosine hydroxylase-immunoreactive network in the nucleus accumbens core and shell.Semantic proximity Read ↗

[Contribution of genetics to the concept of risk status for alcohol dependence].Semantic proximity Read ↗

Strain and cocaine-induced differential opioid gene expression may predispose Lewis but not Fischer rats to escalate cocaine self-administration.Semantic proximity Read ↗

[Biological mechanisms of individual predisposition to psychoactive drug abuse].Semantic proximity Read ↗

Drug addictions. Molecular and cellular endpoints.Semantic proximity Read ↗

Individual difference in addiction-like behaviors and choice between cocaine versus food in Heterogeneous Stock ratsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.