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Article

Vertical shifts in self-administration dose-response functions predict a drug-vulnerable phenotype predisposed to addiction.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jun 2000

Piazza P V, Deroche-Gamonent V, Rouge-Pont F, Le Moal M

Abstract excerpt

The role of individual differences in the etiology of addiction is a very controversial issue. Neuroendocrine phenotypes that are able to predispose an individual to the development of drug intake have been identified previously. However, such information has been gathered by comparing individuals who differ in their sensitivity to low doses of the drug. Consequently, it remains unclear whether a phenotype...

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Identifiers

PMID: 10818158
PMCID: PMC6772616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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