Article
Genes and addiction.
Nature genetics - 1 Nov 2000
Nestler E J
Abstract excerpt
Drug addiction, like all psychiatric disorders, is defined solely in behavioural terms. For example, addiction can be considered a loss of control over drug-taking, or compulsive drug-seeking and -taking despite horrendous consequences. Abnormal behaviours are a consequence of aberrant brain function, which means that it is a tangible goal to identify the biological underpinnings of addiction. The genetic basis...
Topics
- Alcoholism
- Alleles
- Animals
- Behavior, Animal
- Genetic Linkage
- Genetic Predisposition to Disease
- Genetic Techniques
- Genetics, Behavioral
- Humans
- Mice
- Mice, Inbred Strains
- Models, Animal
- Neurotransmitter Agents
- Quantitative Trait, Heritable
- Rats
- Rats, Inbred Strains
- Risk
- Substance-Related Disorders
