Article
Prolonged activation of virus-specific CD8+T cells after acute B19 infection.
PLoS medicine - 1 Dec 2005
Isa Adiba, Kasprowicz Victoria, Norbeck Oscar, Loughry Andrew, Jeffery Katie, Broliden Kristina, Klenerman Paul, Tolfvenstam Thomas, Bowness Paul
Abstract excerpt
BACKGROUND: Human parvovirus B19 (B19) is a ubiquitous and clinically significant pathogen, causing erythema infectiosum, arthropathy, transient aplastic crisis, and intrauterine fetal death. The phenotype of CD8+ T cells in acute B19 infection has not been studied previously. METHODS AND FINDINGS: The number and phenotype of B19-specific CD8+ T cell responses during and after acute adult infection was studied...
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