Article
Genomic scans for selective sweeps using SNP data.
Genome research - 1 Nov 2005
Nielsen Rasmus, Williamson Scott, Kim Yuseob, Hubisz Melissa J, Clark Andrew G, Bustamante Carlos
Abstract excerpt
Detecting selective sweeps from genomic SNP data is complicated by the intricate ascertainment schemes used to discover SNPs, and by the confounding influence of the underlying complex demographics and varying mutation and recombination rates. Current methods for detecting selective sweeps have little or no robustness to the demographic assumptions and varying recombination rates, and provide no method for...
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