Article
The association of astrocytoma and pituitary adenoma in a patient with alcaptonuria.
Journal of the neurological sciences - 1 Mar 1992
Abs R, Van Vyve M, Willems P J, Neetens I, Van der Auwera B, Van den Ende E, Van de Kelft E, Beckers A, Van Marck E, Martin J J
Abstract excerpt
A female patient with a juvenile pilocytic astrocytoma and a pituitary adenoma is described. The patient also has alcaptonuria, a rare inborn error of metabolism with autosomal recessive mode of inheritance. The association of these three disorders has never been reported previously. The possible existence of a common genetic factor in the development of both tumors and alcaptonuria is discussed.
Topics
- Adenoma
- Adult
- Alkaptonuria
- Astrocytoma
- Brain Neoplasms
- Cranial Fossa, Posterior
- Female
- Genes, Tumor Suppressor
- Genetic Predisposition to Disease
- Humans
- Neoplasms, Multiple Primary