Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Finnish HLA studies confirm the increased risk conferred by HLA-B27 homozygosity in ankylosing spondylitis.

Annals of the rheumatic diseases - 1 Jun 2006

Jaakkola E, Herzberg I, Laiho K, Barnardo M C N M, Pointon J J, Kauppi M, Kaarela K, Tuomilehto-Wolf E, Tuomilehto J, Wordsworth B P, Brown M A

Abstract excerpt

OBJECTIVE: To determine the influence of HLA-B27 homozygosity and HLA-DRB1 alleles in the susceptibility to, and severity of, ankylosing spondylitis in a Finnish population. METHODS: 673 individuals from 261 families with ankylosing spondylitis were genotyped for HLA-DRB1 alleles and HLA-B27 heterozygosity/homozygosity. The frequencies of HLA-B27 homozygotes in probands from these families were compared with the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Finland
Share to Histocompatibility Testing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-B27 Antigen

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Logistic Models

Share to Risk Assessment

Share to Spondylitis, Ankylosing

Source

Open in PubMed Open full text

Identifiers

PMID: 16249228
DOI: 10.1136/ard.2005.041103
PMCID: PMC1798178

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Finnish HLA studies confirm the increased risk conferred by HLA-B27 homozygosity in ankylosing spondylitis.PMID 16249228Read ↗

HLA-B27 homozygosity has no influence on clinical manifestations and functional disability in ankylosing spondylitis.Semantic proximity Read ↗

Association of HLA-B27 with ankylosing spondylitis and clinical features of the HLA-B27-associated ankylosing spondylitis: a meta-analysis.Semantic proximity Read ↗

Role of HLA class I and II alleles in susceptibility to ankylosing spondylitis in Chinese Han.Semantic proximity Read ↗

Higher risk of uveitis and dactylitis and older age of onset among ankylosing spondylitis patients with HLA-B*2705 than patients with HLA-B*2704 in the Chinese population.Semantic proximity Read ↗

Influence of HLA-B27 on the Ankylosing Spondylitis phenotype: results from the REGISPONSER databaseSemantic proximity Read ↗

Association of HLA-B27 genetic polymorphisms with ankylosing spondylitis susceptibility worldwide: a meta-analysis.Semantic proximity Read ↗

HLA alleles and HLA-B27 haplotypes associated with susceptibility and severity of ankylosing spondylitis in a Portuguese population.Semantic proximity Read ↗

Non-HLA genes in ankylosing spondylitis: what meta-analyses have shown?Semantic proximity Read ↗

Correlation of HLA B27 subtypes with clinical features of ankylosing spondylitis.Semantic proximity Read ↗

Major histocompatibility genes and ankylosing spondylitis.Semantic proximity Read ↗

Role of HLA-B27 in the pathogenesis of ankylosing spondylitisSemantic proximity Read ↗

Does HLA-B27 Status Influence Ankylosing Spondylitis Phenotype?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.