Article
[Analysis of polymorphic variants of gene GIPC1 CGG repeats in healthy individuals and in patients with breast cancer and non-small cell lung cancer].
Genetika - 1 Sept 2005
Mikhaĭlenko D S, Liubchenko L N, Zborovskaia I B, Strel'nikov V V, Zaletaev D V
Abstract excerpt
The GIPC1 gene product promotes clustering of some transmembrane receptors, including those involved in carcinogenesis, and protects them against ubiquitin-dependent degradation. The 5' untranslated region of GIPC1 contains a polymorphic trinucleotide CGG repeat, which has not been characterized earlier. In the present study, we have carried out comparative analysis of the allele and genotype frequencies of this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.