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Article

The even-skipped locus is contained in a 16-kb chromatin domain.

Developmental biology - 1 Jul 1999

Sackerson C, Fujioka M, Goto T

Abstract excerpt

The even-skipped (eve) gene of Drosophila melanogaster is a crucial member of the pair-rule class of segmentation genes. We report here the characterization of a 16-kb region sufficient for all known aspects of eve expression and the rescue of an eve null mutation. We began by examining 45 kb surrounding the eve coding sequence for DNaseI hypersensitive sites and other transcription units. We find that the...

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Identifiers

PMID: 10373303
DOI: 10.1006/dbio.1999.9301

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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The even-skipped locus is contained in a 16-kb chromatin domain.PMID 10373303Read ↗

Drosophila Paired regulates late even-skipped expression through a composite binding site for the paired domain and the homeodomain.Semantic proximity Read ↗

Natural variation of the expression pattern of the segmentation gene even-skipped in melanogaster.Semantic proximity Read ↗

Regulation of two pair-rule stripes by a single enhancer in the Drosophila embryo.Semantic proximity Read ↗

Analysis of an even-skipped rescue transgene reveals both composite and discrete neuronal and early blastoderm enhancers, and multi-stripe positioning by gap gene repressor gradients.Semantic proximity Read ↗

Spatial specificity of mesodermal even-skipped expression relies on multiple repressor sites.Semantic proximity Read ↗

Molecular integration of inductive and mesoderm-intrinsic inputs governs even-skipped enhancer activity in a subset of pericardial and dorsal muscle progenitors.Semantic proximity Read ↗

Nipped-B, a Drosophila homologue of chromosomal adherins, participates in activation by remote enhancers in the cut and Ultrabithorax genes.Semantic proximity Read ↗

Multiple regulatory elements direct the complex expression pattern of the Drosophila segmentation gene paired.Semantic proximity Read ↗

even skipped is required to produce a trans-acting signal for larval neuroblast proliferation that can be mimicked by ecdysone.Semantic proximity Read ↗

Neural precursor-specific expression of multiple Drosophila genes is driven by dual enhancer modules with overlapping function.Semantic proximity Read ↗

The ventral and posterior expression of the zebrafish homeobox gene eve1 is perturbed in dorsalized and mutant embryos.Semantic proximity Read ↗

Complex regulation of early paired expression: initial activation by gap genes and pattern modulation by pair-rule genes.Semantic proximity Read ↗

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