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Article

Cytochrome P450s: creating novel ligand sets.

Dalton transactions (Cambridge, England : 2003) - 7 Nov 2005

Seward Harriet E, Girvan Hazel M, Munro Andrew W

Abstract excerpt

Cytochromes P450 are a ubiquitous group of hemoproteins that perform vital cellular reactions in all lifeforms. Until recently, it was thought that P450s contained non-covalently bound heme. However, it was established that covalent linkage of the heme macrocycle occurs naturally in one major group of the P450 superfamily. The reaction involves heme linkage to a conserved amino acid and is autocatalytic,...

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Identifiers

PMID: 16234920
DOI: 10.1039/b505362p

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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