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Article

A pH-dependent molten globule transition is required for activity of the steroidogenic acute regulatory protein, StAR.

The Journal of biological chemistry - 16 Dec 2005

Baker Bo Y, Yaworsky Dustin C, Miller Walter L

Abstract excerpt

The steroidogenic acute regulatory protein (StAR) simulates steroid biosynthesis by increasing the flow of cholesterol from the outer mitochondrial membrane (OMM) to the inner membrane. StAR acts exclusively on the OMM, and only StAR's carboxyl-terminal alpha-helix (C-helix) interacts with membra...

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Source

Identifiers

PMID: 16234239
DOI: 10.1074/jbc.M510241200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16234239-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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A pH-dependent molten globule transition is required for activity of the steroidogenic acute regulatory protein, StAR.PMID 16234239Read ↗

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