Article
Avian flu: isolation of drug-resistant H5N1 virus.
Nature - 20 Oct 2005
Le Q Mai, Kiso Maki, Someya Kazuhiko, Sakai Yuko T, Nguyen T Hien, Nguyen Khan H L, Pham N Dinh, Ngyen Ha H, Yamada Shinya, Muramoto Yukiko, Horimoto Taisuke, Takada Ayato, Goto Hideo, Suzuki Takashi, Suzuki Yasuo, Kawaoka Yoshihiro
Abstract excerpt
The persistence of H5N1 avian influenza viruses in many Asian countries and their ability to cause fatal infections in humans have raised serious concerns about a global flu pandemic. Here we report the isolation of an H5N1 virus from a Vietnamese girl that is resistant to the drug oseltamivir, which is an inhibitor of the viral enzyme neuraminidase and is currently used for protection against and treatment of...
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