[Central fat deposits contribute to atherosclerosis and insulin resistance and peripheral fat deposits protect against atherosclerosis and insulin resistance in postmenopausal women--secondary publication].

Abstract excerpt

An analysis of 290 postmenopausal women, subdivided into four distinct body fat distribution groups, showed that peripheral fat mass (PFM) confers insulin-sensitizing and anti-atherogenic effects. PFM contributes to circulating adiponectin, an adipocyte-derived hormone with insulin-sensitizing, anti-inflammatory, and anti-atherogenic effects. In generally obese women, the secretion of adiponectin by PFM provides...

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