A framework to analyze multiple time series data: a case study with Streptomyces coelicolor.

Abstract excerpt

Transcriptional regulation in differentiating microorganisms is highly dynamic involving multiple and interwinding circuits consisted of many regulatory genes. Elucidation of these networks may provide the key to harness the full capacity of many organisms that produce natural products. A powerful tool evolved in the past decade is global transcriptional study of mutants in which one or more key regulatory genes...

Topics

• Anthraquinones
• Anti-Bacterial Agents
• Bacterial Proteins
• Calcium
• Gene Expression Profiling
• Gene Expression Regulation, Bacterial
• Image Processing, Computer-Assisted
• Macrolides
• Mutation
• Oligonucleotide Array Sequence Analysis
• Prodigiosin
• Proteome
• Streptomyces coelicolor