Article
A major bristle QTL from a selected population of Drosophila uncovers the zinc-finger transcription factor poils-au-dos, a repressor of achaete-scute.
Developmental biology - 1 Dec 2005
Gibert Jean-Michel, Marcellini Sylvain, David Jean R, Schlötterer Christian, Simpson Pat
Abstract excerpt
Traditional screens aiming at identifying genes regulating development have relied on mutagenesis. Here, we describe a new gene involved in bristle development, identified through the use of natural variation and selection. Drosophila melanogaster bears a pattern of 11 macrochaetes per heminotum. From a population initially sampled in Marrakech, a strain was selected for an increased number of thoracic...
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