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Article

Polyarticular osteoarthritis--two major phenotypes hypothesized.

Medical hypotheses - 1 Jan 2006

Carroll Graeme J

Abstract excerpt

Osteoarthritis is the commonest form of arthritis, at least amongst Caucasians and is frequently polyarticular. Genetic factors are now considered pivotal in the aetiopathogenesis of polyarticular osteoarthritis (POA). This document proposes a nexus between the gene most commonly mutated amongst Caucasian peoples, notably the HFE gene and an appreciable subset of POA patients who have a clinically recognisable OA...

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Identifiers

PMID: 16213101
DOI: 10.1016/j.mehy.2005.08.028

Genes

HFE
PIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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