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Article

Expression of complement factor H binding immunoevasion proteins in <i>Borrelia garinii </i>isolated from patients with neuroborreliosis

1 Oct 2005

Abstract excerpt

The Lyme disease-pathogen Borrelia burgdorferi binds the complement inhibitor factor H (FH) to its outer surface protein E- (OspE) and BbA68-families of lipoproteins. In earlier studies, only serum-resistant strains of the genospecies B. burgdorferi sensu stricto or B. afzelii, but not serum-sensitive B. garinii strains, have been shown to bind FH. Since B. garinii often causes neuroborreliosis in man, we have...

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Identifiers

PMID: 16208765
DOI: 10.1002/eji.200526354

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