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Article

A novel murine gene, Sickle tail, linked to the Danforth's short tail locus, is required for normal development of the intervertebral disc.

Genetics - 1 Jan 2006

Semba Kei, Araki Kimi, Li Zhengzhe, Matsumoto Ken-ichirou, Suzuki Misao, Nakagata Naoki, Takagi Katsumasa, Takeya Motohiro, Yoshinobu Kumiko, Araki Masatake, Imai Kenji, Abe Kuniya, Yamamura Ken-ichi

Abstract excerpt

We established the mutant mouse line, B6;CB-SktGtAyu8021IMEG (SktGt), through gene-trap mutagenesis in embryonic stem cells. The novel gene identified, called Sickle tail (Skt), is composed of 19 exons and encodes a protein of 1352 amino acids. Expression of a reporter gene was detected in the notochord during embryogenesis and in the nucleus pulposus of mice. Compression of some of the nuclei pulposi in the...

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Identifiers

PMID: 16204209
DOI: 10.1534/genetics.105.048934
PMCID: PMC1456172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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A novel murine gene, Sickle tail, linked to the Danforth's short tail locus, is required for normal development of the intervertebral disc.PMID 16204209Read ↗

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