Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Transcription Factor Pokemon: A New Key Player in Cancer Pathogenesis

1 Oct 2005

Abstract excerpt

Learning how critical cell regulatory pathways are controlled may lead to new opportunities for cancer treatment. We recently identified the transcription factor Pokemon as a central regulator of the important tumor suppressor ARF. Pokemon is overexpressed in multiple human cancers and cells lacking Pokemon are refractory to oncogenic transformation. These findings suggest that Pokemon may offer an effective new...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to RNA modifications and cancer
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16204018
DOI: 10.1158/0008-5472.can-05-1055

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Transcription Factor Pokemon: A New Key Player in Cancer PathogenesisPMID 16204018Read ↗

Overexpression of Pokemon in non-small cell lung cancer and foreshowing tumor biological behavior as well as clinical resultsSemantic proximity Read ↗

Pro-oncogene Pokemon promotes breast cancer progression by upregulating survivin expressionSemantic proximity Read ↗

Proto-oncogene FBI-1 Represses Transcription of p21CIP1 by Inhibition of Transcription Activation by p53 and Sp1Semantic proximity Read ↗

Non-Canonical Functions of the ARF Tumor Suppressor in Development and TumorigenesisSemantic proximity Read ↗

Signalling: uncovering new functions of PI3K mutations.Semantic proximity Read ↗

The master regulator FUBP1: its emerging role in normal cell function and malignant developmentSemantic proximity Read ↗

Signaling via PINCH: Functions, binding partners and implications in human diseasesSemantic proximity Read ↗

Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin.Semantic proximity Read ↗

Emerging functions of p21‐activated kinases in human cancer cellsSemantic proximity Read ↗

An extended β-finger motif is near-ubiquitous in kinase fusion proteinsSemantic proximity Read ↗

PIN1, the cell cycle and cancerSemantic proximity Read ↗

Tribbles: A family of kinase-like proteins with potent signalling regulatory functionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.