Article
Reduction of pneumonia risk by an angiotensin I-converting enzyme inhibitor in elderly Japanese inpatients according to insertion/deletion polymorphism of the angiotensin I-converting enzyme gene.
American journal of hypertension - 1 Oct 2005
Takahashi Takashi, Morimoto Shigeto, Okaishi Kohya, Kanda Tsugiyasu, Nakahashi Takeshi, Okuro Masashi, Murai Hiroshi, Nishimura Yukiharu, Iwai Kunimitsu, Matsumoto Masayuki
Abstract excerpt
BACKGROUND: We have reported that use of angiotensin I-converting enzyme (ACE) inhibitor, which is a class of antihypertensive agent that induces cough, is an independent factor in reducing risk of pneumonia among elderly inpatients. Insertion/deletion (I/D) polymorphism of the ACE gene (ACE) has been associated with the risk of pneumonia in elderly individuals. However, the ability of ACE inhibitors to reduce...
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