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Potential targets of transforming growth factor-beta1 during inhibition of oocyte maturation in zebrafish

30 Sept 2005

Abstract excerpt

BACKGROUND: TGF-beta is a multifunctional growth factor involved in regulating a variety of cellular activities. Unlike mammals, the function of TGF-beta in the reproduction of lower vertebrates, such as fish, is not clear. Recently, we showed that TGF-beta1 inhibits gonadotropin- and 17alpha, 20beta-dihydroxyprogesterone (DHP)-induced maturation in zebrafish. The aim of the present study was to investigate the...

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PMID: 16197550
DOI: 10.1186/1477-7827-3-53

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