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Effects of bone morphogenic protein 4 (BMP4) and its inhibitor, Noggin, on in vitromaturation and culture of bovine preimplantation embryos

1 Feb 2011

Abstract excerpt

BACKGROUND: BMP4 is a member of the transforming growth factor beta (TGFbeta) superfamily and Noggin is a potent BMP inhibitor that exerts its function by binding to BMPs preventing interactions with its receptors. The aim of this work was to investigate the role of BMP4 and Noggin, on oocytes in vitro maturation (m experiments) and embryos in vitro development (c experiments) of bovine. METHODS: For m...

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PMID: 21281523
DOI: 10.1186/1477-7827-9-18

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