Article
Expression of the insulin receptor-related receptor is induced by the preovulatory surge of luteinizing hormone in thecal-interstitial cells of the rat ovary.
Endocrinology - 1 Jan 2006
Dissen Gregory A, Garcia-Rudaz Cecilia, Tapia Veronica, Parada Luis F, Hsu Sheau-Yu Teddy, Ojeda Sergio R
Abstract excerpt
The insulin receptor-related receptor (IRR) is a member of the insulin receptor family that, on its own, recognizes neither insulin nor any of the identified insulin-related peptides. In both the nervous system and peripheral tissues, IRR mRNA is detected in cells that also express trkA, the nerve growth factor tyrosine kinase receptor. In the ovary, the trkA gene is transiently activated in thecal-interstitial...
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