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Article

Mutations at codons 54 and 82 of HIV protease predict virological response of HIV-infected children on salvage lopinavir/ritonavir therapy.

The Journal of antimicrobial chemotherapy - 1 Dec 2005

Luis Jiménez José, Resino Salvador, Martinez-Colom Alberto, Bellón Jose Ma, Angeles Muñoz-Fernández Ma

Abstract excerpt

BACKGROUND: Lopinavir/ritonavir is a protease inhibitor (PI) that has shown great effectiveness as salvage therapy in PI-experienced HIV-infected children. OBJECTIVES: To study whether mutations in the HIV-1 protease gene can reliably predict virological responses to salvage therapy with lopinavir/ritonavir in HIV-infected children. PATIENTS AND METHODS: We carried out a prospective study in 56 HIV-infected...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16195257
DOI: 10.1093/jac/dki356

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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