Article
[Association of angiotensin II receptor type 1 gene single nucleotide polymorphism with Chinese essential hypertension complicated with coronary heart disease].
Zhonghua xin xue guan bing za zhi - 1 Aug 2005
Zhang Kui-xing, Liu Tong-bao, Xu Qiu-xia, Zhu Ding-liang, Huang Wei
Abstract excerpt
OBJECTIVE: To identify the genetic variants of angiotensin II type 1 receptor (AT1) gene in a population of Han ethnicity in east China and to determine whether the AT1 gene polymorphisms are associated with essential hypertension (EH) and coronary heart disease (CHD). METHODS: The detection of single nucleotide polymorphisms (SNPs) was performed in 20 subjects by a direct DNA sequencing. All 213 EH patients, 171...
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