Article
Somatosensory function in asymptomatic Parkin-mutation carriers.
European journal of neurology - 1 Mar 2010
Gierthmühlen J, Schumacher S, Deuschl G, Fritzer E, Klein C, Baron R, Helmchen C
Abstract excerpt
BACKGROUND AND PURPOSE: It is a matter of debate whether somatosensory abnormalities in Parkinson's disease (PD) precede or follow PD motor signs and whether they are of central or peripheral origin. The sensory sural nerve action potential amplitude (SNAP) was previously reported to be reduced in symptomatic Parkin-associated PD. The aim of our study was to investigate asymptomatic Parkin-mutation carriers to...
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