Article
The contractile phenotype of peritubular smooth muscle cells is locally controlled: possible implications in male fertility.
Contraception - 1 Oct 2005
Romano Francesca, Tripiciano Antonella, Muciaccia Barbara, De Cesaris Paola, Ziparo Elio, Palombi Fioretta, Filippini Antonio
Abstract excerpt
The contractile activity of peritubular tissue is responsible for the propulsion of spermatozoa along the lumen of seminiferous tubules toward the hilum of the testis. This function is performed by specialized contractile cells [peritubular smooth muscle cells (PSMC)] in response to the locally produced agonist, endothelin (ET). Here, we review current information on the complex ET-mediated control of peritubular...
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