Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

X chromosome array-CGH for the identification of novel X-linked mental retardation genes.

European journal of medical genetics - 1 Jan 2000

Bauters Marijke, Van Esch Hilde, Marynen Peter, Froyen Guy

Abstract excerpt

Array-CGH technology for the detection of submicroscopic copy number changes in the genome has recently been developed for the identification of novel disease-associated genes. It has been estimated that submicroscopic genomic deletions or duplications will be present in 5-7% of patients with idiopathic mental retardation (MR). Since 30% more males than females are diagnosed with MR, we have developed a full...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Aberrations
Share to Chromosomes, Human, X
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Dosage

Share to Genetic Variation

Share to Nucleic Acid Hybridization

Share to Oligonucleotide Array Sequence Analysis

Share to X-Linked Intellectual Disability

Source

Identifiers

PMID: 16179222
DOI: 10.1016/j.ejmg.2005.04.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

X chromosome array-CGH for the identification of novel X-linked mental retardation genes.PMID 16179222Read ↗

Detection of genomic copy number changes in patients with idiopathic mental retardation by high-resolution X-array-CGH: important role for increased gene dosage of XLMR genes.Semantic proximity Read ↗

High-resolution genomic microarrays for X-linked mental retardation.Semantic proximity Read ↗

X-chromosome tiling path array detection of copy number variants in patients with chromosome X-linked mental retardation.Semantic proximity Read ↗

X-linked mental retardation: many genes for a complex disorder.Semantic proximity Read ↗

Int22h-1/int22h-2-mediated Xq28 rearrangements: intellectual disability associated with duplications and in utero male lethality with deletions.Semantic proximity Read ↗

Detection of chromosomal imbalances in children with idiopathic mental retardation by array based comparative genomic hybridisation (array-CGH).Semantic proximity Read ↗

Chromosomal microarray analysis (CMA) detects a large X chromosome deletion including FMR1, FMR2, and IDS in a female patient with mental retardation.Semantic proximity Read ↗

Duplication of the MECP2 region is a frequent cause of severe mental retardation and progressive neurological symptoms in males.Semantic proximity Read ↗

Array CGH identifies reciprocal 16p13.1 duplications and deletions that predispose to autism and/or mental retardation.Semantic proximity Read ↗

X-linked mental retardation: a comprehensive molecular screen of 47 candidate genes from a 7.4 Mb interval in Xp11.Semantic proximity Read ↗

Identification of an X-linked deletion syndrome through comparative genomic hybridization microarray.Semantic proximity Read ↗

XLMR genes: update 1992.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.