Article
Pan1p, an actin cytoskeleton-associated protein, is required for growth of yeast on oleate medium.
Experimental cell research - 1 Nov 2005
Kamińska Joanna, Wysocka-Kapcińska Monika, Smaczyńska-de Rooij Iwona, Rytka Joanna, Zoładek Teresa
Abstract excerpt
Pan1p is a yeast actin cytoskeleton-associated protein localized in actin patches. It activates the Arp2/3 complex, which is necessary for actin polymerization and endocytosis. We isolated the pan1-11 yeast mutant unable to grow on oleate as a sole carbon source and, therefore, exhibiting the Oleate- phenotype. In addition, mutant cells are temperature-sensitive and grow more slowly on glycerol or...
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