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Article

Complement factor B allotypes in the susceptibility and severity of coeliac disease in patients and relatives.

International journal of immunogenetics - 1 Oct 2005

da Rosa Utiyama S R, da Silva Kotze L M, de Messias Reason I T

Abstract excerpt

The alternative pathway of complement plays an important role in the pathogenesis of coeliac disease (CD), where factor B (BF) is central to its activation. CD is a gluten-sensitive enteropathy that results from a complex interplay between genetic, immunologic, and environmental factors. In this study we evaluated the association of BF allotypes with the susceptibility and severity of CD, and with the presence of...

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PMID: 16164698
DOI: 10.1111/j.1744-313X.2005.00529.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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