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Article

Polymorphism of p16 INK4A and cyclin D1 in adenocarcinomas of the upper gastrointestinal tract.

Journal of cancer research and clinical oncology - 1 Dec 2005

Geddert Helene, Kiel Sibylle, Zotz Rainer B, Zhang Jianhui, Willers Reinhart, Gabbert Helmut E, Sarbia Mario

Abstract excerpt

PURPOSE: We investigated the prevalence of single nucleotide polymorphisms in the p16 gene (C540G) and the cyclin D1 gene (G870A), both known to regulate function in G1 arrest and therefore, may play an important role in carcinogenesis. METHODS: Using PCR based restriction fragment length polymorphism and single strand conformational polymorphism, we determined single nucleotide exchanges in the p16 and cyclin D1...

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PMID: 16163549
DOI: 10.1007/s00432-005-0021-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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