Article
Severe neutropenia in Japanese patients with x-linked agammaglobulinemia.
Journal of clinical immunology - 1 Sept 2005
Kanegane Hirokazu, Taneichi Hiromichi, Nomura Keiko, Futatani Takeshi, Miyawaki Toshio
Abstract excerpt
X-linked agammaglobulinemia (XLA) is clinically characterized by recurrent bacterial infections during early infancy. Although it is not a phagocytic disorder, XLA is sometimes associated with neutropenia. We conducted a nation-wide survey to determine the frequency of neutropenia among Japanese XLA patients. Responses were received from 87 (86%) of 101 patients in which BTK mutations were previously identified,...
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