Computed tomographic images reflect the biologic behavior of small lung adenocarcinoma: they correlate with cell proliferation, microvascularization, cell adhesion, degradation of extracellular matrix, and K-ras mutation.

doi:10.1016/j.jtcvs.2005.05.013

Article

Computed tomographic images reflect the biologic behavior of small lung adenocarcinoma: they correlate with cell proliferation, microvascularization, cell adhesion, degradation of extracellular matrix, and K-ras mutation.

The Journal of thoracic and cardiovascular surgery - 1 Sept 2005

Dong Boming, Sato Masami, Sakurada Akira, Sagawa Motoyasu, Endo Chiaki, Wu Shulin, Yamanaka Sumitaka, Horii Akira, Kondo Takashi

Abstract excerpt

BACKGROUND: We previously reported that the computed tomographic M/L ratio (area of the tumor in the mediastinal computed tomographic image/area of the tumor in the lung computed tomographic image) of small peripheral lung adenocarcinoma is correlated with patient prognosis. METHODS: Immunostaining for p53, bcl-2, Ki-67, vascular endothelial growth factor, CD34, matrix metalloproteinase 2, matrix...

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