Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Preferential Survival of CD4+ T Lymphocytes Engineered with Anti-Human Immunodeficiency Virus (HIV) Genes in HIV-Infected Individuals

1 Sept 2005

Abstract excerpt

The present study examined the safety and relative in vivo survival of genetically engineered CD4+ T lymphocytes in human immunodeficiency virus (HIV)-infected individuals. Ten pairs of identical twins discordant for HIV infection were recruited, with the uninfected twin serving as the lymphocyte donor. Ten subjects were treated with a total of 19 separate infusions of retroviral vector-transduced CD4+ enriched T...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16149905
DOI: 10.1089/hum.2005.16.1065

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Preferential Survival of CD4+ T Lymphocytes Engineered with Anti-Human Immunodeficiency Virus (HIV) Genes in HIV-Infected IndividualsPMID 16149905Read ↗

Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIVSemantic proximity Read ↗

Expression of a protective gene-prolongs survival of T cells in human immunodeficiency virus-infected patients.Semantic proximity Read ↗

A Controlled, Phase 1 Clinical Trial to Evaluate the Safety and Effects in HIV-1 Infected Humans of Autologous Lymphocytes Transduced with a Ribozyme that Cleaves HIV-1 RNA. University of California San Diego, La Jolla, CaliforniaSemantic proximity Read ↗

Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice.Semantic proximity Read ↗

Long‐term survival and concomitant gene expression of ribozyme‐transduced CD4+ T‐lymphocytes in HIV‐infected patientsSemantic proximity Read ↗

In Vivo Suppression of HIV by Antigen Specific T Cells Derived from Engineered Hematopoietic Stem CellsSemantic proximity Read ↗

Selective survival of peripheral blood lymphocytes in children with HIV-1 following delivery of an anti-HIV gene to bone marrow CD34+ cellsSemantic proximity Read ↗

Survival of the Fittest: Positive Selection of CD4+ T Cells Expressing a Membrane-Bound Fusion Inhibitor Following HIV-1 InfectionSemantic proximity Read ↗

Gene Therapy in Peripheral Blood Lymphocytes and Bone Marrow for ADA <sup>−</sup> Immunodeficient PatientsSemantic proximity Read ↗

Regulated expression of a dominant negative form of Rev improves resistance to HIV replication in T cells.Semantic proximity Read ↗

A Rev-inducible mutant gag gene stably transferred into T lymphocytes: an approach to gene therapy against human immunodeficiency virus type 1 infection.Semantic proximity Read ↗

Analysis of Lentiviral Vector Integration in HIV+ Study Subjects Receiving Autologous Infusions of Gene Modified CD4+ T CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.