Article
Use of pyrosequencing to differentiate Streptococcus pneumoniae serotypes 6A and 6B.
Journal of clinical microbiology - 1 Sept 2005
Pai Rekha, Limor Josef, Beall Bernard
Abstract excerpt
Accurate serotyping of Streptococcus pneumoniae remains important to monitor the changes in seroepidemiology of the organism over time. Though several PCR-based systems have been developed for this purpose, the cross-reactivity within serogroups often limits discrimination between types. All serogroup 6 isolates can be identified using a multiplex PCR system; however, due to the high sequence homology between the...
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